| Sa, 04.09.21, 16:00h | HSG Alten/Buke 2 | SG HB Detmold | |
| So, 12.09.21, 18:00h | TV Hor-Bad Mei | HSG Alten/Buke 2 | |
| Sa, 18.09.21, 15:30h | HSG Alten/Buke 2 | VfL Schlangen | |
| Sa, 23.10.21, 16:00h | HSG Alten/Buke 2 | TuS SG Sennel | |
| Sa, 06.11.21, 16:15h | HB Bad Salzuf. 2 | HSG Alten/Buke 2 | |
| Sa, 13.11.21, 15:30h | HSG Alten/Buke 2 | HSG Hb Lemgo 3 | |
| Sa, 04.12.21, 17:30h | TSV Bösingfeld | HSG Alten/Buke 2 | |
| Sa, 11.12.21, 16:00h | HSG Alten/Buke 2 | HSG Blom-Lippe | |
| Sa, 18.12.21, 16:00h | HSG Alten/Buke 2 | HC Steinheim | |
| Sa, 15.01.22, 18:00h | SGS Aug/Hövel | HSG Alten/Buke 2 | |
| Sa, 22.01.22, 19:00h | SG HB Detmold | HSG Alten/Buke 2 | |
| Sa, 29.01.22, 16:00h | HSG Alten/Buke 2 | TV Hor-Bad Mei | |
| So, 13.02.22, 18:00h | VfL Schlangen | HSG Alten/Buke 2 | |
| Sa, 05.03.22, 17:30h | TuS SG Sennel | HSG Alten/Buke 2 | |
| Sa, 12.03.22, 15:30h | HSG Alten/Buke 2 | HB Bad Salzuf. 2 | |
| Sa, 26.03.22, 16:00h | HSG Hb Lemgo 3 | HSG Alten/Buke 2 | |
| Sa, 02.04.22, 16:00h | HSG Alten/Buke 2 | TSV Bösingfeld | |
| Sa, 23.04.22, 19:00h | HSG Blom-Lippe | HSG Alten/Buke 2 | |
| Sa, 30.04.22, 17:00h | HC Steinheim | HSG Alten/Buke 2 | |
| Sa, 07.05.22, 16:00h | HSG Alten/Buke 2 | SGS Aug/Hövel | |